Managing Cancer during Pregnancy by Hatem A. Azim Jr

Author:Hatem A. Azim Jr
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

Antibiotics

It is widely known that there is an increased risk of infection in patients receiving chemotherapy. This is mainly due to neutropenia caused by the toxic effect of chemotherapy on the bone marrow. This complication adds complexity to treatment especially if the patient is a pregnant woman. Antibiotics, such as penicillins (beta-lactamase-sensitive and beta-lactamase-resistant penicillins, beta-lactamase inhibitor), cephalosporins, carbapenems, and the most of macrolides (azithromycin, erythromycin, and spiramycin), are approved by FDA as category B, and their use is recommended during pregnancy. Table 8.2 summarizes the safety of the most commonly used antibiotics [20].

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